Cerdelga (Eliglustat) is indicated for long-term treatment of Gaucher’s disease. It is a genetic disorder in which glucocerebroside accumulates in cells and certain organs. Glucocerebroside is a sphingolipid, also known as glucosylceramide.
This medication can improve symptoms of Gaucher’s disease such as:
- Pain in the bones/joints
- A swollen liver/spleen
How does Cerdelga (Eliglustat) work?
Cerdelga (Eliglustat) works by blocking the action of an enzyme involved in the production of the glucosylceramide fat. It is because the build-up of this fat in organs like the liver, spleen, and bones is responsible for the symptoms of type-1 Gaucher’s disease. It reduces its production by helping it prevent its build-up. And thereby it helps the affected organs to function better.
Why use Cerdelga (Eliglustat)?
Cerdelga (Eliglustat) is a small molecule inhibitor of glucosylceramide synthase. Glucosylceramide synthase is an enzyme that results in the reduced making of glucocerebroside. It is a fatty substance that unusually accumulates in the cells and tissues of those with Gaucher’s disease.
This contains Eliglustat as an active ingredient. Each capsule contains 84mg of Eliglustat which is equivalent to 100mg of Cerdelga in one capsule. This is indicated for oral use. The Food and Drug Administration (FDA) has already approved this medication.
How to use Cerdelga (Eliglustat)?
Cerdelga (Eliglustat) is to be taken by mouth with a full glass of water. It is usually taken once or twice a day. You should not crush or chew the capsule swallow it as a whole. To help you remember, take it at the same time every day.
The dosage is based on your condition, response, and other medications you may be taking.
What are the side-effects of Cerdelga (Eliglustat)?
- Headache or migraine
- Joint pain
- Mouth or throat pain
- Back pain
- Abdominal pain
- Pain in the extremities
Warnings and Precautions
- Before using this drug, discuss with your doctor the risks and benefits of this.
- Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding while taking this medication.
- Tell your doctor if you are allergic to it or if you have any allergies. This drug may contain an inactive ingredient that may cause an allergic reaction or other problem.
- Do not drive or do anything that requires your alertness. This drug may make you feel dizzy.
- Limit alcoholic beverages.
- This should not be used by people with liver problems. And also for those taking certain medications that can interfere with the ability of the body to break down the medicine.
- Tell your doctor if you have any medical history.