Exported Medicines

Glucotrol XL (Glipizide)

Glucotrol XL (Glipizide)

General Information

Glucotrol XL (Glipizide) is used to control high blood sugar in people with type 2 diabetes. It used along with a proper diet and exercise. It may also be used in combination with other diabetes medicines.

Controlling high blood sugar may prevent blindness and kidney damage. It may also prevent sexual function problems, nerve problems, and loss of limbs. Proper control of diabetes may lessen your risk of stroke and heart attack.

How does Glucotrol XL (Glipizide) work?

Glucotrol XL (Glipizide) mainly lowers blood sugar. It is by stimulating the release of insulin from the pancreas. It is an effect dependent upon functioning beta cells in the pancreatic islets. This medication binds to its receptor in the pancreatic beta-cell plasma membrane. That it leads to closure of the ATP-sensitive potassium channel. Thereby, it stimulates the release of insulin.

Why use Glucotrol XL (Glipizide)?

Glucotrol XL is an oral drug that contains an active ingredient of Glipizide. It belongs to the class of medications known as a sulfonylurea. It is a whitish and odorless powder. It is supplied as an extended-release tablet with the strengths of 2.5 mg, 5 mg, and 10 mg. The U.S. Food and Drug Administration (FDA) has approved this medication.

How to use Glucotrol XL (Glipizide)?

This drug is to be taken usually once a day by mouth. As directed by your doctor it is to be taken with breakfast. The dosage is based on your condition and response to it.  

Swallow the tablet as a whole. Do not break or chew it. It may increase the risk of side effects. Don’t forget to take it at the same time every day. Take each dose exactly as it is prescribed.

What are the side-effects of Glucotrol XL (Glipizide)?

Common side effects:

  • Vomiting
  • Nausea
  • Diarrhea
  • Loss of appetite
  • Upset stomach
  • Constipation
  • Dizziness
  • Gas
  • Headache
  • Dizziness
  • Weight gain
  • Skin rash, itching, or redness

Let your doctor know if these serious side effects occur:

  • Easy bleeding or bruising
  • Yellowing eyes or skin
  • Stomach pain
  • Signs of an infection (fever and persistent sore throat)
  • Dark urine
  • Swelling of hands or feet
  • Unusual weakness or tiredness
  • Sudden or unusual weight gain

Warnings and Precautions

  • Inform your doctor if you have any medical history or current medications.
  • Tell also to your doctor if you have any allergies. Call for medical help right away in case there are signs of an allergic reaction.
  • Limit alcohol while taking this medicine. It can increase your risk of developing low blood sugar.
  • This drug may make you more sensitive to the sun. Limit your time in the sun.
  • This prescription should only be used when clearly needed in pregnant women.