Idhifa (Enasidenib) is indicated to treat a certain type of blood cell cancer called acute myeloid leukemia. AML is a cancer of the myeloid line of blood cells. It is characterized by the rapid growth of abnormal cells. That is build up in the bone marrow and blood. It interferes with normal blood cells. This type of condition typically treated with chemotherapy. This medication will help your bone marrow grow normal blood cells. It is to help you also need a fewer blood transfusion.
How does Idhifa (Enasidenib) work?
Idhifa (Enasidenib) is a small molecule inhibitor of the isocitrate dehydrogenase 2 (IDH2) enzymes. It targets the mutant IDH2 variants. Inhibition of the mutant IDH2 enzyme by this drug led to decreased 2-hydroxyglutarate (2-HG) levels. It also leads to an induced myeloid differentiation. This medication lessens 2-HG levels, reduced blast counts and increased percentages of mature myeloid cells.
Why use Idhifa (Enasidenib)?
Idhifa (Enasidenib) is an inhibitor of isocitrate dehydrogenase-2 (IDH2) enzyme. It comes as a tablet for oral use. Each tablet contains Enasidenib as an active ingredient. It is available in the strengths of 50 mg and 100 mg. The Food and Drug Administration (FDA) has already approved this medicine.
How to use Idhifa (Enasidenib)?
Idhifa (Enasidenib) is to be taken by mouth with a full glass of water. It is usually taken once a day. Swallow the tablet as a whole. Do not break or chew it. You may take it with or without food. The recommended dosage is based on your medical condition and response to it.
Take each dose exactly as it is prescribed. Do not take it more often or longer than the prescription. Remember to take it at the same time and in the same way each day.
What are the side-effects of Idhifa (Enasidenib)?
- Decreased appetite
- Changes in taste
Warnings and Precautions
- Before taking each dose, tell your doctor if you are allergic to it. This drug may contain an inactive ingredient that causes an allergic reaction.
- If you are pregnant or breastfeeding women, consult your doctor first before taking this drug.
- Do not use this drug past the expiration date.
- You should not share this prescription with others even if they have the same symptoms as yours.
- Inform your doctor if you have a medical history or current medications.
- Keep this away from the reach of children.