Siponimod is used for the treatment of relapsing multiple sclerosis (MS). In relapsing multiple sclerosis, the central nervous system which includes the spinal cord and brain is damaged. MS causes the immune system to attack the myelin which is the insulation protecting the nerves. This medication helps prevent the immune system cells from attacking the nerves in your spinal cord and brain.
How does Siponimod work?
Siponimod binds with high affinity to S1P receptors. This blocks the capability of lymphocytes to egress from lymph nodes. It also lessens the number of lymphocytes in peripheral blood. The mechanism by which Siponimod exerts therapeutic effects in multiple sclerosis is unidentified. But it may involve the reduction of lymphocyte migration into the central nervous system.
Why use Siponimod?
Siponimod is a sphingosine 1-phosphate (S1P) receptor modulator. This helps lessen the number of episodes of disease worsening or relapses. Siponimod may also prevent or delay disability. This is a prescription approved by the U.S. Food and Drug Administration (FDA). This medication comes as a tablet for oral use. Each tablet is available in strengths of 0.25 mg and 2 mg that contains Siponimod.
How to use Siponimod?
The dosage depends on your medical condition, age, and response. Your doctor may direct you to start this at a low dose and gradually increase it. Follow your doctor’s instructions carefully.
Siponimod is usually taken once a day. It is to be taken by mouth with a full glass of water. You may take each dose with or without food. Don’t forget to take each dose at the same time each day. For the best benefit, take it regularly. Do not take more or less than it is given by your doctor.
What are the side effects of Siponimod?
Common side effects:
- Swelling of extremities
- Pain in the extremities
- High blood pressure
- Increased transaminase
If these side effects persist or get worse, call your doctor right away.
Warnings and Precautions
- Do not stop taking Siponimod without consulting your doctor.
- Tell your doctor if you are allergic to this drug before using.
- Inform your doctor if you have any medical history or current medications (herbal remedies or vitamins).
- If you are pregnant or breastfeeding women, consult your doctor first.
- You should not share this or any of our medications with others even if they have the same symptoms as yours.
- Keep this at a dry and clean place far from heat and moisture.