Exported Medicines

Sufentanil

Sufentanil

Where is Sufentanil used?

Sufentanil is a prescription medication used for the treatment of serious fungal infections. This can also be used to prevent invasive fungal infections in people who have had a bone marrow transplant. 

This is a type of medicine called a triazole antifungal that helps treats the infections caused by fungi. Sufentanil is an FDA-approved medication that comes as a sublingual tablet for oral use.

How does Sufentanil work?

Sufentanil works by preventing fungi from making a substance called ergosterol. The cell membranes of fungi are important for their existence. They preserve unwanted substances from entering the cells and stop the substances of the cells from leaking out. Without ergosterol as part of the cell membrane, the membrane is weakened and essential constituents of the fungal cells can leak out. This kills the fungi and hence clears up the infections.

How is Sufentanil taken?

The dosage is based on your medical condition and response to the treatment. Sufentanil is to be taken by mouth usually twice a day, every 12 hours. Each dose may be taken at least an hour before or an hour after a meal. It is important to take the medicine regularly for the best benefit. Take each dose at the same time and in the same way each day.

Even if you feel better, do not suddenly stop this medication until your doctor tells you to do so. Stopping it suddenly may increase the chance that the infection will come back and that the fungi will grow resistant to the medicine. Some people may need to take Sufentanil for a long time especially those hard-to-treat infections or bone marrow transplant recipients taking this to prevent infections.

What are the possible side effects of Sufentanil?

  • Headache
  • Nausea
  • Dizziness
  • Vomiting

Call your doctor right away if these side effects occur:

  • Unusual tiredness or weakness
  • Poor coordination
  • Muscle stiffness
  • Loss of appetite
  • Fainting 
  • Blurred vision
  • Difficulty with swallowing

What are the precautions in using Sufentanil?

  • Before starting this medication, you will need to have a blood test to measure the levels of electrolytes in your blood. If there are any problems, your doctor will give you treatment to correct them before you start taking this drug.
  • Your skin may be more sensitive to sunlight. For this reason, you must avoid exposing your skin to sunlight during treatment. If you will be going outside, you should cover exposed areas of skin with clothing or use sunscreen with a high protection factor. 
  • This can sometimes cause liver problems. For this reason, your liver function will be checked before taking Sufentanil. 
  • This should be used with caution in people with liver cirrhosis, recently had cancer chemotherapy, any long-term disorder that affects the muscle of the heart, or with an irregular heartbeat. 
  • Sufentanil is not recommended for use in pregnant, breastfeeding women, and in children under 2 years of age. 
  • Tell your doctor if you are allergic to this drug or if you have any allergies. This drug might have an ingredient that causes an allergic reaction. If there are any signs, call for medical help right away.