Exported Medicines

Canagliflozin and Metformin Hydrochloride

Canagliflozin and Metformin Hydrochloride

General Information

Invokamet XR is the brand name of this combined medication. This contains Canagliflozin and Metformin Hydrochloride used in the management of type II diabetes. This is to be used with a proper diet and exercise in people with high blood sugar.

Controlling high blood sugar helps prevent loss of limbs, kidney damage, and blindness. It also prevents nerve problems and sexual function problems. Proper control of diabetes may also lessen your risk of stroke and heart attack.

How does Canagliflozin and Metformin Hydrochloride work?

Canagliflozin and Metformin Hydrochloride work by:

  • Helping to restore your body’s proper response to the insulin that you naturally create
  • Increasing the removal of sugar by your kidneys
  • Lessens how much sugar that is made by your liver
  • Decreases how much sugar your body takes in through your intestines and stomach

Why use Canagliflozin and Metformin Hydrochloride?

Canagliflozin and Metformin Hydrochloride is an inhibitor of sodium-glucose cotransporter 2 (SGLT2). This helps you to lose about 100 grams of sugar a day. The transporter is responsible for reabsorbing the majority of glucose filtered by the kidney. The Food and Drug Administration (FDA) has already approved this medication.

Invokamet XR is supplied as film-coated tablets for oral use. Each tablet is available in the strengths of:

  • 50 mg-500 mg
  • 50 mg-1000 mg
  • 150 mg-500 mg
  • 150 mg-1000 mg

How to use Canagliflozin and Metformin Hydrochloride?

This medication is usually taken twice a day with food. Each dose is to be taken by mouth with a full glass of water. Do not break or chew the tablet. Swallow it whole. Remember to take it at the same time every day.

If you missed a dose, take it as soon as you remember. But if it is almost time for the next dose, skip the missed dose. Do not double the dosage.

What are the side-effects of Canagliflozin and Metformin Hydrochloride?

  • Diarrhea
  • Vomiting
  • Nausea
  • Weakness
  • Increased urination
  • Abdominal discomfort
  • Thirst
  • Headache
  • Thirst
  • Vaginal itching
  • Genital yeast infections
  • Urinary tract infections

Warnings and Precautions

  • While having this prescription, do not drink alcohol. It drops the blood sugar level and may increase the risk of lactic acidosis.
  • You may be more likely to have broken bone while using this medicine. Talk to your doctor about how to avoid the risk of fractures.
  • Tell your doctor if you have any medical history, current medications, or allergies.
  • Consult your doctor first if you are pregnant or breastfeeding women.