Exported Medicines

Depakene (Valproic Acid)

Depakene (Valproic Acid)

General Information

Depakene (Valproic Acid) is indicated for the treatment of a certain type of seizures or epilepsy. This is also used to treat the manic phase of bipolar disorder or manic-depressive illness. This helps prevent migraine and headaches. Depakene (Valproic Acid) is sometimes used together with other seizure medications.

How does Depakene (Valproic Acid) work?

Depakene (Valproic Acid) uses its effects by increasing the absorption of gamma-aminobutyric acid (GABA) in the brain. It is a neurotransmitter, a chemical that nerves use to communicate with one another.

This medication works by restoring the balance of certain natural substances or neurotransmitters in the brain.


Why use Depakene (Valproic Acid)?

Depakene has Valproic Acid as an active ingredient. Each soft elastic capsule contains 250mg of Valproic Acid for oral administration. This drug belongs to the group of medications known as anticonvulsants. In the year 1978, the Food and Drug Administration (FDA) has approved this medication.

How to use Depakene (Valproic Acid)?

The dosage is based on your weight, age, condition, and response. This medication is to be taken by mouth as directed by your doctor. You may take it with or without food. Do not chew or crush the capsule, swallow it as a whole.

For seizures, the dose is a 10-15mg/kg/day. There is an increased by 5-10mg/kg/day every week to achieve the desired result. The response is usually seen when the blood concentration of this drug is 50-100mcg/ml.

For acute mania due to bipolar disorder, the starting dose is at 750mg per day of delayed-release tablets in divided doses. The maximum dose is 60mg/kg/day.

For migraines, the dose is 250mg twice a day. The maximum recommended dose is 1000mg per day. When using extended-release tablets, the recommended dose is 500-1000mg given once a day.

Use this regularly or exactly as it is prescribed. Take it at the same time each day.

What are the side-effects of Depakene (Valproic Acid)?

  • Constipation
  • Dizziness
  • Weakness
  • Double or blurred vision
  • Enlarged breasts
  • Shakiness or tremor
  • Weight changes
  • Diarrhea
  • Upset stomach
  • Drowsiness
  • Hair loss
  • Changes in menstrual periods
  • Ringing in the ears
  • Unsteadiness
  • Unusual or unpleasant taste in your mouth

Warnings and Precautions

  • Before taking this medication, talk with your doctor about the risks and benefits of this drug.
  • Tell your doctor if you have any allergies.
  • This is not prescribed for pregnant women. If you are breastfeeding women, consult your doctor first.
  • This drug may make you feel dizzy. Avoid using any machinery or driving.