General Information

Desmopressin Acetate is used to control the amount of urine that your kidney makes. Usually, the amount of urine you make is controlled by a certain substance in the body called vasopressin. In people who have ‘water diabetes’ or certain kinds of head injury, the body does not make enough vasopressin. Desmopressin Acetate may also help to prevent dehydration.

How does Desmopressin Acetate work?

Desmopressin Acetate is in the class of medications called antidiuretic hormones. It is similar to a hormone that is produced in the body. It is to help balance the amount of water and salt. This medication acts on the kidneys to lessen the flow of the urine.

Why use Desmopressin Acetate?

Desmopressin Acetate is a man-made form of vasopressin. This is used to replace a low level of vasopressin. This may also help to control increased thirst and too much urination. Desmopressin Acetate is a white powder that is freely soluble in water. This is soluble in alcohol and glacial acetate acid. This medication is formulated for intranasal use without preservatives.

Desmopressin Acetate nasal spray is available as an oil-in-water emulsion at two dose strengths; 0.83 mcg and 1.66 mcg. Each spray has 0.1 ml of Desmopressin Acetate. This is a prescription approved by the Food and Drug Administration (FDA).

How to use Desmopressin Acetate?

The dosage is based on your medical condition and response to the treatment. This is to be taken exactly as it is given by your doctor. You should not take in a larger or smaller amount.

Spray this medication in the nose usually 1 to 3 times a day or as directed. If the dose is more than 1 spray, spray half the dose in each nostril. If the dose is 2 sprays, give 1 spray in each nostril. Call your doctor if your condition does not improve.

What are the side effects of Desmopressin Acetate?

• Runny or stuffy nose
• Nasal discomfort
• Elevated or high blood pressure
• Sneezing
• Nosebleed
• Back pain
• Dizziness
• Painful or difficult urination

Warnings and Precautions

• While using this medication, limit drinking water or other fluids especially in children or older adults.
• Limit alcohol. It may interfere with how well Desmopressin Acetate works.
• Tell your doctor if you are allergic to it before using.
• Tell as well if you are taking another medication.
• Do not share this or any of your drugs with others even if they have the same symptoms as yours.
• Keep this far from the reach of children.