Doravirine

What condition does Doravirine treat?

Doravirine is a medication used to help control HIV infection. This is used along with other HIV prescriptions. This helps to reduce the HIV in your body so your immune system can work better.

HIV medications can’t cure the infection, but taking a combination of HIV medications each day helps people live longer and have a healthier life. HIV medications also lessen the risk of HIV transmission. If you are taking HIV medications, don’t cut down on, skip, or stop taking them unless your doctor tells you to.

Doravirine is an antiretroviral drug. This is a pyridinone non-nucleoside reverse transcriptase inhibitor of HIV infection. This has been already approved by the Food and Drug Administration (FDA). This is available as film-coated tablets for oral administration.

How does Doravirine work?

Doravirine inhibits the HIV reverse transcriptase enzyme in the virus. It results in the inhibition of HIV replication. HIV reverse transcriptase enzyme has a vital role in the duplication of the virus in the body. The medicine does not stop other enzymes such as human cellular DNA polymerases and mitochondrial DNA polymerase.

What is the recommended dosage of Doravirine?

The recommended dosage is based on your condition and response.

This is usually taken once a day. It is to be taken by mouth with a full glass of water. You may take it with or without food. It is important to take HIV medications exactly as it is prescribed. You should not keep any doses. To help you remember, take it at the same time every day.                        

Do not change the dosage or stop taking this without checking first with your doctor. When your supply is running low, contact your pharmacist ahead of time. Do not let yourself run out of this medicine.

Keep taking this medication for the full time of treatment even if you begin to feel better. It is also vital that you continue to take all of the medications that have been given you for the infection.

What are the side effects of Doravirine?

  • Dizziness
  • Nausea
  • Headache
  • Diarrhea
  • Fatigue
  • Abnormal dreams
  • Abdominal pain
  • Insomnia

What are the precautions in taking Doravirine?

  • Always use an effective barrier method during sexual activity (latex or condoms)
  • Do not share personal items that may have contacted blood or other body fluids (toothbrush, razors, or syringes)
  • You should not share this medication with others even if they have the same symptoms as yours.
  • If you are a pregnant or breastfeeding woman, consult your doctor first before taking this drug.
  • Proper studies have not been accomplished on the relationship of age to the effects of this drug in the pediatric population. Safety and efficiency have not been established.
  • Certain medications should not be used at or around the time of eating food since interactions may occur. Using tobacco or alcohol with other drugs might also cause interactions to befall. Talk with your doctor about the use of your medication with tobacco, alcohol, or food.
  • Inform your doctor if you ever had an allergic reaction to this medicine or any other medicines.