Guanfacine

What condition does Guanfacine treat?

Guanfacine is used for the treatment of attention deficit hyperactivity disorder (ADHD). This prescription is used as part of the overall treatment plan including psychological, educational, and social measures. This is used alone or along with other ADHD medications. It may help reduce ADHD symptoms such as being:

  • Hyperactive
  • Disruptive
  • Inattentive
  • Impulsive
  • Arguing with adults
  • Losing one’s temper  

ADHD is a mental disorder of the neurodevelopmental type. It is characterized by excessive activity and difficulty paying attention. It is also characterized by behavior without regard to consequences. In which it is not appropriate for a person’s age.

Guanfacine is a centrally-acting and alpha-adrenergic receptor agonist. This product is supplied as tablets for oral administration. In the year 1986, the Food and Drug Administration (FDA) has approved this medication.

How does Guanfacine work?

Guanfacine selectively stimulates central alpha-adrenergic receptors. It results in an inhibition of sympathetic vasomotor centers. In which it contributes predominantly to the hypotensive effects of the medication. A central effect of this drug leads to reduced peripheral sympathetic nerve impulses. It is from the vasomotor center to the blood vessels and heart.

This results in reduced peripheral vascular resistance. It also decreases heart rate. The stimulation of this drug may also contribute to hypotensive effects.

What is the recommended dosage for Guanfacine?

This medicine is to be taken by mouth with a full glass of water, usually taken once a day in the morning or evening. You may take each dose with or without a meal. Do not take each dose with a high-fat meal. It may increase the amount you absorb and leads to an increased risk of side effects.

The dosage is based on your medical condition and response to it. Remember to take each dose at the same way and time each day. Take it exactly as it is prescribed.

What are the side effects of Guanfacine?

  • Dizziness
  • Drowsiness
  • Constipation
  • Dry mouth
  • Nausea
  • Tiredness
  • Stomach pain
  • Headache
  • Irritability
  • Weight gain

Tell your doctor if you have these serious side effects:

  • Slow heartbeat
  • Severe dizziness
  • Fainting
  • Mental/mood changes (hallucinations or thought of suicide)

What are the precautions in taking Guanfacine?

  • Before using this drug, tell your doctor your medical history especially of kidney or liver disease.
  • Let your doctor know if you are allergic to this medicine or if you have any allergies.
  • Do not suddenly stop or change the dosage of this medication without consulting your doctor.
  • Call your doctor right away if the side effects continue or get worse.
  • Inform your doctor if you are taking other medicines like vitamins or herbal supplements.
  • Do not switch between different forms of this medication without talking with your doctor. Different forms of this drug may not provide the same amount of Guanfacine.
  • Children may be more sensitive to the side effects of this drug, especially mental/mood changes and hallucinations.
  • During pregnancy, this medicine should be used only when needed. Discuss the risks and benefits with your doctor.
  • It is unknown if this medicine passes into breastmilk. Discuss the risks and benefits with your doctor before breastfeeding.