Ibritumomab Tiuxetan

What condition does Ibritumomab Tiuxetan treat?

Ibritumomab Tiuxetan is used along with rituximab for the treatment of B-cell non-Hodgkin’s lymphoma. In this type of disease, the tumors develop from lymphocytes which are a type of white blood cell.

This medicine is a monoclonal antibody. A monoclonal antibody is a type of protein that has been designed to recognize and bind to a specific structure called an antigen. It is specifically found in certain cells in the body. The Food and Drug Administration (FDA) has already approved this prescription.

How does Ibritumomab Tiuxetan work?

Ibritumomab Tiuxetan has been designed to target an antigen. It is present on the surface of all B lymphocytes. When this drug is radiolabelled, the radioactive element yttrium 90 is attached to this drug. Once the radiolabelled drug is injected into the patient, the monoclonal antibody transmits the radioactivity to the aim CD20 antigen on the B cells. Once the antibody has bound to the antigen, the radiation can act locally. It also destroys the lymphoma B cells.

What is the recommended dosage for Ibritumomab Tiuxetan?

The amount of this medication that you will receive depends on lots of factors including your overall health, height and weight, and the type of condition being treated.  Your doctor will conclude your dosage and schedule. It is important to have this medication exactly as it is prescribed. Do not take more than or more often than the prescription.

This medication is to be given by injection into a vein by a doctor or healthcare professional. This should be given regularly. If you missed a dose, call your doctor right away. Do not have twice the dosage to make up for the missed dose.

What are the side effects of Ibritumomab Tiuxetan?

  • Vomiting
  • Nausea
  • Stomach pain
  • Diarrhea
  • Dizziness
  • Upset cough
  • Loss of appetite
  • Flushing
  • Joint pain
  • Anxiety
  • Tiredness
  • Fever
  • Throat weakness
  • Inflammation of the nose

If these side effects persist or worsen, call your doctor right away.

What are the precautions in taking Ibritumomab Tiuxetan?

  • Before taking this medicine, tell your doctor if you are allergic to it. This drug may have an inactive substance that causes an allergic reaction.
  • Do not drive or do any activity that needs your alertness. This medication may make you feel dizzy.
  • You might be at risk of infection. For this reason, try to avoid people with colds or not feeling well, and report any signs of infection especially fever right away to your health care provider.
  • If you are a pregnant or breastfeeding woman, consult your doctor first.
  • Your red and white blood cells and platelets may temporarily reduce. This can put you at increased risk for anemia, infection, or bleeding. If this occurs, call your health care provider right away.
  • Do not receive any kind of vaccination or immunization without your doctor’s approval while taking this medication.
  • Drinking alcoholic beverages should be kept to a minimum or avoided completely.  Alcohol may increase certain side effects while having this drug. You should discuss this with your doctor.