Exported Medicines

Oxaprozin

Oxaprozin

Where is Oxaprozin used?

Oxaprozin is used for the treatment of osteoarthritis and rheumatoid arthritis. This may also be used in pediatric patients as young as 6 years for the treatment of juvenile idiopathic arthritis (JIA).

This belongs to the group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). This is available for oral administration. This was originally approved in the year 1992 by the Food and Drug Administration (FDA).

How does Oxaprozin work?

The anti-inflammatory effect of Oxaprozin is believed to be due to the inhibition of cyclooxygenase in platelets. In which it is the one that leads to the blockage of prostaglandin synthesis. Antipyretic effects may be due to action on the hypothalamus. This results in increased peripheral blood flow, vasodilation, and subsequent heat dissipation. This medication is a non-selective NSAID.

Oxaprozin works by decreasing the levels of prostaglandins and chemicals that are responsible for fever, pain, and inflammation. This medication stops the enzyme that creates prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a result, fever, inflammation, and pain are reduced.

How is Oxaprozin taken?

The recommended dosage for this medication depends on your condition and response.

Oxaprozin is usually taken once a day with 600 mg or 1200 mg as the starting dose. The maximum dose is 1800 mg daily. The total daily dose may be divided into multiple doses if single daily doses are not tolerated. Take this medication with food or milk. Take it at the same time each day. Do not lie down for at least 10 minutes after taking the drug.

Drink a full glass of water with it unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking this medicine. If a stomach upset happens while taking this medicine, take it with milk, food, or an antacid. In certain conditions, it may take up to 2 weeks when this medicine is taken regularly before you notice the full benefits. Tell your doctor if your condition worsens.

What are the possible side effects of Oxaprozin?

  • Nausea
  • Heartburn
  • Vomiting
  • Stomach pain
  • Constipation
  • Diarrhea
  • Gas
  • Dizziness
  • Headache
  • Drowsiness
  • Confusion
  • Skin rash
  • Itching
  • Ringing in your ears

What are the precautions in taking Oxaprozin?

  • Do not stop taking this medication without talking with your doctor.
  • You should not give this to anyone else even if they have the same symptoms as yours.
  • This may make you feel dizzy or drowsy. Avoid driving or do anything that needs your alertness.
  • If you are a breastfeeding woman or pregnant, consult your doctor first.
  • Tell your doctor if you have any allergies. Tell also your doctor if you have any medical history especially of asthma, liver disease, or heart disease.
  • Limit your time in the sun. This medication may make you more sensitive to the sun.
  • Proper studies performed to date have not established pediatric-specific complications that would limit the usefulness of this medicine in children 6 to 16 years of age. Safety and effectiveness have not been established in children younger than 6 years of age. Consult your doctor first before giving this to children younger than 6 years of age.