Exported Medicines



Where is Penciclovir used?

Penciclovir is used to treat cold sores caused by the herpes simplex virus. This is used on the lips and faces of adults. This cream can speed up the healing of the sores and decrease symptoms like burning, pain, and itching. This medication does not cure herpes and it will not prevent from passing of the infection to someone else. This will also not prevent future occurrences.

Penciclovir is an antiviral agent active against herpes viruses. This belongs to the class of medications known as antivirals. This is available for topical administration as a white cream. The Food and Drug Administration (FDA) approved this treatment.

How does Penciclovir work?

Penciclovir selectively prevents viral DNA polymerase by opposing deoxyguanosine triphosphate. Inhibition of DNA synthesis of virus-infected cells prevents viral reproduction. In cells not infected with the herpes simplex virus, DNA synthesis is unchanged. Resistant mutants of the herpes simplex virus can occur from qualitative changes in DNA polymerase or viral thymidine kinase. The most usually encountered acyclovir-resistant mutants that are deficient in viral thymidine kinase are also resistant to Penciclovir. This medication stops the growth and development of the virus.

How to use Penciclovir?

Use this medication at the first sign of infection like burning, tingling, sores, or redness.

Wash your hands first with soap and water before applying the cream. Before applying the medication, clean and dry the affected areas. Apply a thin layer of cream to completely cover the cold sore area or the area of itching, tingling, or redness. Then rub it gently. Apply the cream every 2 hours except during sleep. It should be applied for 4 days or as directed by your doctor.

Apply this to the skin only. Do not apply in or near the eyes. This medication may irritate the eyes. If it accidentally gets into your eyes, flush it with plenty of water. You should also not apply this inside the mouth or nose.

What are the possible side effects of Penciclovir?

  • Numbness or tingling where the cream was applied
  • Headache
  • Changes in your sense of taste
  • Application site reaction (skin discoloration, redness, burning, or hives)
  • Swollen mouth or throat

If these side effects persist or get worse, call your doctor for medical assistance.

What are the precautions in using Penciclovir?

  • Stop using this medication and call for medical assistance if there is an allergic reaction.
  • Let your doctor know if you have any medical history or current treatments or medications including food supplements, vitamins, or herbal products.
  • Discuss with your doctor the risks and benefits of this treatment.
  • Let your doctor know if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking this medication, call your doctor.
  • If you missed a dose, apply the missed dose as soon as you remember it and apply any remaining doses for that day at evenly spaced intervals. On the other hand, if it is almost time for your next dosage, never mind the missed one and continue your fixed dosing plan. Do not apply a double dose to make up for a missed one.