Exported Medicines

Rizatriptan Benzoate

Rizatriptan Benzoate

Rizatriptan Benzoate is in the class of drugs known as triptans used to treat migraines. This drug helps relieve pain, headache, and other migraine symptoms; vomiting, nausea, or sensitivity to sound/light. Rizatriptan Benzoate affects certain natural substances that cause the narrowing of blood vessels in the brain. This medication may also relieve pain by affecting certain nerves that are in the brain. Prompt treatment helps you return to your normal routine and may lessen your need for pain medications. Rizatriptan Benzoate has already been approved by the Food and Drug Administration (FDA). This product comes in the form of tablets and is available in the dosage forms of 5 mg and 10 mg. 

Migraine is a type of headache that causes moderate to severe pain. The pain is pulsing or throbbing. It often occurs on one side of your head. Some studies believe that migraine has a genetic cause. Some factors can trigger this kind of condition. These may vary from person to person and they include:

  • Hormonal changes in women
  • Stress
  • Anxiety
  • Loud noises
  • Bright or flashing lights
  • Medicines
  • String smells
  • Sudden changes in the weather or environment
  • Too much or not enough sleep
  • Caffeine or caffeine withdrawal
  • Skipped meals

For some, they have found that certain foods or ingredients can trigger headaches. It may include:

  • Chocolate
  • Alcohol
  • Some fruits and nuts
  • Yeast
  • Fermented or pickled goods 

Migraine is a powerful headache that can last from 4 hours to 3 days and sometimes longer. This starts when overactive nerve cells send out signals that activate the trigeminal nerve. It is the nerve that supplies sensation to your head and face. The activation of the nerve may cause the release of certain chemicals called CGRP. CGRP is a calcitonin gene-related peptide that causes blood vessels in the lining of the brain to swell. This releases neurotransmitters that create inflammation and pain. Some signs and symptoms of this condition may include:

  • Inability to perform regular activities due to pain
  • Increasing pain during physical activity or when straining
  • Increased sensitivity to sound and light, only relieved by lying quietly in a darkened room
  • Moderate to severe pain usually confined to one side of the head but capable of occurring on either side of the head 
  • Feeling sick and physically vomiting 

How does this medication work?

Rizatriptan Benzoate stimulates receptors called serotonin or 5HT receptors. These receptors are found in the brain. A natural substance called serotonin usually acts on these receptors. Wherein, it causes blood vessels in the brain to narrow. Rizatriptan Benzoate imitates the action of serotonin. It is by directly stimulating the serotonin receptors that are in the brain. This narrows the blood vessels and therefore relieves the pain of migraines. 

How to use this medicine?

Rizatriptan Benzoate is a prescription taken at the first sign of a migraine. Take it by mouth as directed by your doctor. Each dose may be taken with or without food. Take the tablet with a full glass of water. Remember to take it in the same way and at the same time each day. It may as well work faster when it is taken on an empty stomach. The recommended dosage is based on your medical condition and response to the treatment. For children, the dosage is based on their weight. 

If there is no improvement in your symptoms, do not take more doses of this drug. Adults may take another dose at least 2 hours after the first dose. It is if your symptoms are only partially relieved. For children, they should not take more than one dose or 5 milligrams in 24 hours. If you are using medications for migraine attacks on 10 or more days each month, the drug may make your headaches worse. You should not use medications more often or for longer than it is directed by your doctor. Let your doctor know if this medication is not working well or if your condition gets worse. Call as well your doctor if there happened to be 4 headaches in a month. 

Possible side effects of Rizatriptan Benzoate:

  • Dry mouth
  • Mild headache
  • Pressure or heavy feeling in any part of your body
  • Feeling pain or tightness in the neck, jaw, or throat
  • Dizziness
  • Tired feeling
  • Drowsiness
  • Weakness
  • Flushing (redness, warmth, or tingling feeling under your skin)
  • Feelings of numbness, prickling, heat, or tingling 

Stop using the drug and call your doctor right away if these occur:

  • Cold feeling or numbness in your feet and hands
  • Sudden and severe stomach pain
  • Bloody diarrhea
  • Heart attack symptoms (sweating, nausea, chest pain, pain that spreads to your shoulder or jaw)
  • High levels of serotonin in your body (diarrhea, vomiting, nausea, fainting, loss of coordination, or agitation)
  • Dangerously high blood pressure (blurred vision, severe headache, chest pain, anxiety, uneven heartbeats, or buzzing in your ears)

Things to remember while taking Rizatriptan Benzoate:

  • This should only be used by people with a clear diagnosis of migraine from their doctor. 
  • The drug may cause feelings of heaviness or pressure that may only last a few minutes. If they continue, you should not take any tablets anymore and consult your doctor right away. 
  • This may cause drowsiness. Do not operate machinery or drive if you are affected. 
  • Rizatriptan Benzoate should be used with caution in people with decreased liver or kidney function, with risk factors for coronary heart disease, in men over 40 years of age, and in post-menopausal women. 
  • In people with heart disease, who have had a heart attack, poor blood circulation, and uncontrolled high blood pressure, this prescription should not be used. 
  • This product may have lactose and should not be taken by people with rare hereditary problems of galactose intolerance. 
  • Rizatriptan Benzoate is not recommended for children and adolescents aged less than 18 years or people aged over 65 years. There is no information available regarding its safety and effectiveness in this age group.
  • Let your doctor know if you have current medications including herbal supplements or vitamins. 
  • Keep this product at room temperature.