Where is Tamoxifen Citrate used?
Tamoxifen Citrate is used for the treatment of breast cancer. This medicine attaches to the hormone receptor in the cancer cell that blocks the estrogen from attaching to the receptor. By blocking, it slows the growth of the tumor by preventing the cancer cells from getting the hormones they need to grow. Tamoxifen Citrate is a nonsteroidal anti-estrogen that the FDA has already approved.
How does Tamoxifen Citrate work?
Tamoxifen Citrate works by blocking estrogen receptors. In that way, it blocks the effect of estrogen on breast cancer cells. This stops the cancer cells from growing.
Most breast cancers are sensitive to estrogen and their growth is increased in the presence of this hormone. Estrogen binds to estrogen receptors on the breast cancer cells. That causes changes within the cells that result in faster growth of cancer. Breast cancers that are sensitive to estrogen are called estrogen receptor-positive cancers.
How is Tamoxifen Citrate taken?
Tamoxifen Citrate is usually taken once or twice a day for 5 years. This is to be taken by mouth. Everyday doses of more than 20 milligrams are typically divided in half and taken twice a day. Each dose may be taken in the morning and evening. The recommended dosage is based on your medical condition and response to the treatment. Do not take more or less than it is given. Your doctor may direct you to start at a lower dose and eventually increase it. Let your doctor know if your condition worsens or does not improve.
Do not suddenly stop taking Tamoxifen Citrate without the consent of your doctor. Even if you feel well, continue to take the medication until the full prescription is done. To help you remember, take the drug at the same time and in the same way each day. Drink plenty of fluids while having this treatment. Doing so may lessen the risk of certain side effects.
What are the possible side effects of Tamoxifen Citrate?
- Leg cramps
- Hair thinning
- Muscle aches
- Changes in menstrual periods
- Weight loss
- Loss of sexual ability/interest
Call your doctor right away if these side effects occur:
- Blurred vision, eye pain, or seeing halos around lights
- Changes in your menstrual periods
- A new breast lump
- High levels of calcium in your blood
What are the precautions in taking Tamoxifen Citrate?
- Tell your doctor if you have any medical history or current medications (prescriptions or non-prescription).
- If you are allergic to it, tell it your doctor right away before using it. This medication may contain an inactive ingredient that causes an allergic reaction.
- Consult your doctor first if you have a medical history of high blood pressure, liver disease, or blood clots.
- Inform your doctor if you are pregnant or plan to become pregnant. If you are breastfeeding women, consult your doctor first.
- Women who are pregnant or who may become pregnant must not handle this medicine.
- If you are taking Tamoxifen Citrate to reduce your risk of breast cancer, you may need to take your first dose while you are having a menstrual period. Before you start taking tamoxifen, you may also need to have a pregnancy test.