Exported Medicines

Trecator (Ethionamide)

Trecator (Ethionamide)

General Information

Trecator (Ethionamide) is used for the treatment of tuberculosis (TB). It is a disease caused by bacteria called mycobacterium tuberculosis. It usually attacks the lungs and it can also damage other parts of the body. This medication is usually used along with other tuberculosis medication.

This drug may also be used with other medications to help treat Mycobacterium avium complex-MAC. It may also be used with other medications to prevent the MAC infection from occurring again in people with advanced HIV disease.

How does Trecator (Ethionamide) work?

Trecator (Ethionamide) may be bactericidal in action. It depends on the concentration of the drug attained at the site of infection. It also depends on the susceptibility of the infecting organism. This drug is a nicotinic acid derivative related to isoniazid. It is thought that Ethionamide undergoes intracellular modification. It acts in a similar fashion to isoniazid. Isoniazid inhibits the synthesis of mycoloic acids. It is an essential component of the bacterial cell wall. Specifically, isoniazid inhibits the enoyl reductase from Mycobacterium tuberculosis. It is by forming covalent adducts. It acts as a slow and tight-binding competitive inhibitor. It also works by stopping the growth of the bacteria.


Why use Trecator (Ethionamide)?

Trecator Tablets contains Ethionamide as an active ingredient. It belongs to the group of drugs called anti-tubercular medications. It is a yellow crystalline and practically soluble in methanol and ethanol. This drug has strength of 250 mg for oral use. This was approved by the Food and Drug Administration (FDA).

How to use Trecator (Ethionamide)?

This medication is to be taken by mouth usually once a day. You may take it with or without food. You may take it also with food if the drug causes nausea, vomiting, or stomach upset.

The dosage is based on your medical condition, age, and response. Take it exactly as it is prescribed. Follow all the instruction of your doctor very carefully.


What are the side-effects of Trecator (Ethionamide)?

  • Vomiting
  • Nausea
  • Diarrhea
  • Increased saliva
  • Stomach pain
  • Dizziness
  • Headache
  • Loss of appetite
  • Rash
  • Shaking
  • Unusual fatigue or weakness
  • Sores in the mouth

Call your doctor right away if these side effects persist or worsen.


Warning and Precautions

  • Before taking the drug, let your doctor know if you are allergic to it. Tell also to your doctor if you have any allergies or medical history.
  • While using this medication, avoid alcoholic beverages.
  • This may not be recommended for pregnant women. For breastfeeding, consult your doctor first.
  • Keep this at a dry and clean place.